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Claudia
Holzman, D.V.M., M.P.H., Ph.D.
Associate Professor
Department of Epidemiology
D.V.M,
1976, Michigan State University
M.P.H., 1986, University of Minnesota
Ph.D., 1996, University of Michigan
Address:
Department of Epidemiology
B601 West Fee Hall
Michigan State University
East Lansing, MI 48824
Email: holzman@msu.edu
Telephone: (517) 353-8623 ext.122 |
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Research
Claudia
Holzman, Associate Professor of Epidemiology in the
College of Human Medicine at Michigan State University,
received her Doctor of Veterinary Medicine degree from
Michigan State University in 1976, her Master’s
of Public Health degree from University of Minnesota
in 1986, and her PhD degree in epidemiology from University
of Michigan in 1996. Dr. Holzman has been involved in
reproductive and perinatal research, primarily focusing
on the areas of preterm delivery, brain injury in neonates,
birth defects, and vaginal infections. In her earlier
research, Dr. Holzman led the feasibility study that
resulted in the establishment of a state-wide birth
defects registry in Michigan.
Dr. Holzman currently has two ongoing studies, one on
preterm birth (POUCH Study) funded by the National Institute
of Child Health and Development and the March of Dimes
Birth Defects Foundation, and one on vaginal infections
in non-pregnant women (DAISY Study) funded by the Blue
Cross/Blue Shield of Michigan Foundation. The first
study is a multi-community, prospective study designed
to identify pathways to preterm delivery (e.g. infection,
maternal vascular disease) by assessing psychosocial
and biologic factors in approximately 2,000 pregnant
women. Psychosocial antecedents in the preterm pathways
are measured at the individual (participant interview)
and ecological (community/ neighborhood conditions and
resources) levels. Biologic markers and mediators are
evaluated in maternal serum, plasma, vaginal fluid,
urine, saliva, and hair collected in mid-trimester.
In addition, the study focus includes a detailed examination
of the delivered placenta, linking specific pathologic
findings to various preterm delivery pathways. The second
study, on vaginal infections, is a three-stage investigation
of the epidemiology of bacterial vaginosis (BV). The
study began with a cross-sectional, quantitative assessment
of risk factors for BV in 498 women in the Greater Lansing
Area, and has now progressed to the latter stages- qualitative
research with small focus groups of women who have recurrent
BV and/or who regularly use vaginal douches, and a small
clinical trial to assess the effects of vaginal douching
on changes in vaginal flora.
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